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MEDICATION guide
Nicotine Replacement Therapy

The Nicotine Inhaler

What Is It?
The nicotine inhaler, also nicknamed "the puffer" is a thin, plastic cartridge that contains a porous nicotine plug in its base. By puffing on the cartridge, nicotine vapor is extracted and absorbed through the lining of the mouth. Each cartridge delivers up to 400 puffs of nicotine vapor. It takes at least 80 puffs to obtain the equivalent amount of nicotine delivered by one cigarette.

Temperature affects the amount of nicotine that is extracted from the inhaler device. At cooler temperatures, less nicotine is extractable. Specific information on this aspect is included in the product packaging inserts.

Research on the nicotine inhaler has demonstrated that it nearly doubles quit rates when compared with placebo inhalers. This is similar to other pharmaceutical products, like the patch, the gum and bupropion (Zyban/Wellbutrin SR®).

The nicotine inhaler was made available by prescription in June 1998.

Warnings, Cautions and Various Nasty Possibilities
Like any medication, the inhaler can have negative side effects. The most common side effect of the inhaler is irritation of the lining of the mouth. Less common are coughing, runny nose or upset stomach. These symptoms are generally mild and likely to diminish with regular use.

As in using all other forms of nicotine replacement, if you receive too little nicotine you may experience the symptoms of withdrawal. This can occur either from simply not using the inhaler frequently enough, or by not using it properly.

Using the Nicotine Inhaler
After placing the cartridge into your mouth, puff in either shallow or deep breaths, to bring the vaporized nicotine into the back of your throat. Users are generally instructed to puff frequently, using from 6-16 cartridges per day during the first three months. Users then taper or reduce the number of cartridges during the subsequent 6-12 weeks. The manufacturer states that the inhaler should not be used for longer than 6 months.

Why Choose the Nicotine Inhaler?
Some people prefer the inhaler as a form of nicotine replacement because both the inhaling process and handling the cartridge mimic the behavioral aspects of smoking. Also, the amount of nicotine delivered to and the effects on the user's body resemble those produced by nicotine gum, thereby making the potential for abuse low.

To help you determine if the inhaler is right for you, you may consider using the QuitNet Medication Wizard.

More medically specific information ...

If you think that the Nicotine Inhaler is right for you, see your doctor about a prescription.


Content author: Alan S. Peters, CTTS-M
Reviewed by: Andy Perez, MD, MBA, FACEP, February 2009

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